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Cannabinoids are compounds found in the cannabis plant that can interact with the endocannabinoid system. The most notable cannabinoid is the phytocannabinoid tetrahydrocannabinol (THC) (Delta-9-THC), the primary intoxicating compound in cannabisCannabidiol (CBD) is another major constituent of the some cannabis plants. At least 113 distinct cannabinoids have been isolated from cannabis.


It was reported in 2020 that cannabinoids can be found in other plants such as rhododendron, licorice and liverwort, and earlier in Echinacea.

Classical cannabinoids are structurally related to THC.

Nonclassical cannabinoids (cannabimimetics) include aminoalkylindoles, 1,5-diarylpyrazoles, quinolines, and arylsulfonamides as well as eicosanoids related to endocannabinoids.

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